Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22635667 | 1.00 | ATM (0.48) | ATMALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL20779824 | 0.84 | NPC1 (0.52) | ATMALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL30411362 | 0.84 | NPC1 (0.52) | ATMALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL20766317 | 0.82 | MAPT (0.46) | ATMALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL20779713 | 0.82 | TEAD1 (0.52) | ATMALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL25790320 | 0.81 | TEAD1 (0.43) | ATMALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL20779823 | 0.81 | MAPT (0.45) | ATMALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL25789101 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL30409574 | 0.71 | TNNI3K (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL20766204 | 0.71 | TNNI3K (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691623-B1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS INC (US) | 2022-10-05 | — | — | EP | disclosed |