Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | PARG | Q86W56 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779824 | 1.00 | NPC1 (0.52) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22635667 | 0.84 | ATM (0.48) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29901815 | 0.84 | ATM (0.48) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20766317 | 0.81 | MAPT (0.46) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20779713 | 0.80 | TEAD1 (0.52) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL25790320 | 0.79 | TEAD1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20779823 | 0.79 | MAPT (0.45) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21054687 | 0.79 | RAB9A (0.60) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20766214 | 0.76 | ACLY (0.38) | SMN1; SMN2ALDH1A1CA12CA1CA2 | |
| SCHEMBL29438852 | 0.76 | ACLY (0.38) | SMN1; SMN2ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542315-B | Benzosulfonyl compounds | 维瓦斯治疗公司 | 2023-05-12 | — | — | CN | disclosed |