Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766211 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20766225 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDTHRBLMNA | |
| SCHEMBL20766234 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTHRBLMNA | |
| SCHEMBL20766378 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDTHRBLMNA | |
| SCHEMBL20766607 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDTHRBLMNA | |
| SCHEMBL20767215 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDTHRBLMNA | |
| SCHEMBL20767259 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDTHRBLMNA | |
| SCHEMBL20779653 | 0.78 | ALOX15 (0.46) | ALDH1A1MAPTHPGDTHRBLMNA | |
| SCHEMBL20766200 | 0.77 | MAPT (0.40) | ALDH1A1MAPTHPGDTHRBLMNA | |
| SCHEMBL25789400 | 0.77 | CNR1 (0.42) | ALDH1A1MAPTCYP3A4HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691623-B1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS INC (US) | 2022-10-05 | — | — | EP | disclosed |