Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 5/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FRK | P42685 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23160878 | 0.88 | CSNK1D (0.48) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL29902500 | 0.82 | ADORA2A (0.42) | CSNK1DCSNK1EGRM2KDM4EALDH1A1 | |
| SCHEMBL30499536 | 0.81 | LMNA (0.51) | MAPK14KDM4EALDH1A1HPGDADORA2A | |
| SCHEMBL1257163 | 0.80 | CSNK1D (0.51) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL30136520 | 0.79 | MET (0.41) | CSNK1DGRM2KDM4EALDH1A1HPGD | |
| SCHEMBL29902513 | 0.78 | IRAK4 (0.47) | CSNK1DCSNK1EGRM2KDM4EGSK3B | |
| SCHEMBL22309898 | 0.77 | SLC6A4 (0.50) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL14335004 | 0.75 | IRAK4 (0.51) | GRM2KDM4EALDH1A1HPGDADORA2A | |
| SCHEMBL15328107 | 0.75 | MET (0.50) | GRM2METAXLPTGS1ABCB1 | |
| SCHEMBL9585904 | 0.73 | LMNA (0.54) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625027-B | Heterocyclic derivatives and use thereof | 药捷安康(南京)科技股份有限公司 | 2022-09-09 | — | — | CN | disclosed |