Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | POR | P16435 | 1/20 | 0.46 |
| ▸ | USP8 | P40818 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16527422 | 0.93 | S100A4 (0.57) | S100A4CA1CA2CA4CA7 | |
| SCHEMBL28155812 | 0.88 | CA1 (0.57) | CA1CA2CA4CA7CA9 | |
| SCHEMBL2993382 | 0.84 | CA1 (0.53) | CA1CA2CA4CA7CA9 | |
| SCHEMBL7786812 | 0.84 | CA1 (0.57) | CA1CA2CA4CA7CA9 | |
| SCHEMBL11876117 | 0.82 | S100A4 (0.80) | S100A4IDO1USP8METAP1PTPN1 | |
| SCHEMBL2997273 | 0.81 | PTPN1 (0.54) | S100A4CA1CA2CA4CA7 | |
| SCHEMBL9656985 | 0.81 | ALKBH3 (0.53) | CA1CA2CA4CA7CA9 | |
| SCHEMBL30004012 | 0.81 | ALKBH3 (0.53) | CA1CA2CA4CA7CA9 | |
| SCHEMBL10885799 | 0.80 | CA1 (0.53) | CA1CA2CA4CA7CA9 | |
| SCHEMBL23111388 | 0.80 | CA1 (0.57) | CA1CA2CA4CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100180937-A1 | HOLOGRAPHIC ENERGY-COLLECTING MEDIUM AND ASSOCIATED DEVICE | GENERAL ELECTRIC COMPANY (US) | 2010-07-22 | — | — | US | disclosed |