Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PTPRC | P08575 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111380 | 0.96 | PTPRC (0.59) | PTPN1PTPRCMAPTALDH1A1HPGD | |
| SCHEMBL17439396 | 0.96 | MAPT (0.55) | PTPN1MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL4645032 | 0.92 | PTPN1 (0.58) | PTPN1PTPRCMAPTALDH1A1HPGD | |
| SCHEMBL2993382 | 0.92 | CA1 (0.53) | PTPN1PTPRCMAPTALDH1A1HPGD | |
| SCHEMBL28155812 | 0.92 | CA1 (0.57) | PTPN1MAPTALDH1A1HPGDRAB9A | |
| 2-Methoxyanthraquinone SCHEMBL222927 | 0.90 | PTPN1 (0.60) | PTPN1PTPRCMAPTALDH1A1HPGD | |
| SCHEMBL31669020 | 0.89 | GPR3 (0.59) | PTPN1MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL25693544 | 0.89 | GPR3 (0.59) | PTPN1MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL10885799 | 0.88 | CA1 (0.53) | PTPN1MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL7786812 | 0.87 | CA1 (0.57) | PTPN1MAPTALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155609-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING PTEN INHIBITORS | TRANSFUSION HEALTH LLC | 2020-05-21 | — | — | US | disclosed |
| US-20100180937-A1 | HOLOGRAPHIC ENERGY-COLLECTING MEDIUM AND ASSOCIATED DEVICE | GENERAL ELECTRIC COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155609-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING PTEN INHIBITORS | PTEN, MCL1, PIK3CA | PTPN1 31/4885PTPRC 20/4885MAPT 4692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.