SCHEMBL29903221

SCHEMBL29903221

Cc1cc(C)c(-c2cc(C(C)(C)C)cc(C)c2-c2c(C)cc(C)c(C(=O)O)c2C)c(C)c1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRB P28702 5/20 0.38
ALDH1A1 P00352 6/20 0.35
CYP3A4 P08684 2/20 0.35
ACHE P22303 1/20 0.35
GLRA3 O75311 1/20 0.35
GLRB P48167 1/20 0.35
RXRA P19793 4/20 0.35
RXRG P48443 1/20 0.35
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPK1 P28482 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GRIN2C Q14957 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
DHODH Q02127 1/20 0.33
HPGD P15428 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28655418 0.85 CA12 (0.41) RXRBALDH1A1RXRAKDM4EL3MBTL1
SCHEMBL9815280 0.81 CYP3A4 (0.48) ALDH1A1CYP3A4ACHEGLRA3GLRB
SCHEMBL501930 0.77 RXRB (0.50) RXRBALDH1A1CYP3A4ACHEGLRA3
SCHEMBL28660408 0.75 TTR (0.46) ALDH1A1CYP3A4ACHEKDM4EL3MBTL1
SCHEMBL28664621 0.71 LDHA (0.41) ALDH1A1CYP3A4ACHEL3MBTL1MAPK1
SCHEMBL8106142 0.71 CYP3A4 (0.54) ALDH1A1CYP3A4ACHEGLRA3GLRB
SCHEMBL18493974 0.71 CYP3A4 (0.42) RXRBALDH1A1CYP3A4ACHERXRA
SCHEMBL17781486 0.69 RXRB (0.44) RXRBALDH1A1CYP3A4ACHEGLRA3
Hydrochloric Acid SCHEMBL5042476 0.69 CYP3A4 (0.52) ALDH1A1CYP3A4ACHEGLRA3GLRB
Hydrochloric Acid SCHEMBL5037307 0.69 CYP3A4 (0.52) ALDH1A1CYP3A4ACHEGLRA3GLRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN claimed
CN-110536909-B Method for producing propylene copolymers having a low VOC content 格雷斯公司 2022-08-23 CN claimed
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN disclosed
CN-110536909-B Method for producing propylene copolymers having a low VOC content 格雷斯公司 2022-08-23 CN disclosed