SCHEMBL501930

SCHEMBL501930

Cc1cc(C(C)(C)C)cc(C)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRB P28702 5/20 0.50
CYP3A4 P08684 2/20 0.48
ACHE P22303 1/20 0.48
GLRA3 O75311 1/20 0.48
GLRB P48167 1/20 0.48
RXRA P19793 4/20 0.47
RXRG P48443 1/20 0.47
KDM4E B2RXH2 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 3/20 0.45
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
SRD5A2 P31213 1/20 0.42
MAPT P10636 1/20 0.41
NOTUM Q6P988 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642911 0.88 CYP3A4 (0.50) RXRBCYP3A4ACHEGLRA3GLRB
SCHEMBL5581647 0.86 CYP3A4 (0.48) RXRBCYP3A4ACHEGLRA3GLRB
SCHEMBL17781486 0.86 RXRB (0.44) RXRBCYP3A4ACHEGLRA3GLRB
SCHEMBL25207237 0.84 CYP3A4 (0.47) RXRBCYP3A4ACHEGLRA3GLRB
SCHEMBL27595813 0.82 RXRB (0.39) RXRBCYP3A4ACHEGLRA3GLRB
SCHEMBL501929 0.81 POLB (0.44) RXRBCYP3A4ACHEGLRA3GLRB
SCHEMBL112083 0.81 POLB (0.44) RXRBCYP3A4RXRARXRGKDM4E
SCHEMBL422352 0.79 RXRA (0.51) RXRBCYP3A4ACHERXRARXRG
SCHEMBL6466602 0.79 GLRA3 (0.57) RXRBCYP3A4GLRA3GLRBRXRA
SCHEMBL14760909 0.79 GLRA3 (0.52) RXRBCYP3A4ACHEGLRA3GLRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10930872-B2 Light-emitting electrochemical cell, composition for forming light-emitting layer of light-emitting electrochemical cell, and ionic compound for light-emitting layer of light-emitting electrochemical cell NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 2021-02-23 US disclosed
CN-108293284-B Electrochemical light-emitting cell, composition for forming light-emitting layer of electrochemical light-emitting cell, and ionic compound for light-emitting layer of electrochemical light-emitting cell NIPPON CHEMICAL INDUSTRIAL CO.,LTD. (JP) 2019-12-10 CN disclosed
US-20180301653-A1 LIGHT-EMITTING ELECTROCHEMICAL CELL, COMPOSITION FOR FORMING LIGHT-EMITTING LAYER OF LIGHT-EMITTING ELECTROCHEMICAL CELL, AND IONIC COMPOUND FOR LIGHT-EMITTING LAYER OF LIGHT-EMITTING ELECTROCHEMICAL CELL NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 2018-10-18 US disclosed
EP-3386274-A1 ELECTROCHEMICAL LIGHT EMITTING CELL, COMPOSITION FOR FORMING LIGHT EMITTING LAYER OF ELECTROCHEMICAL LIGHT EMITTING CELL, AND IONIC COMPOUND FOR LIGHT EMITTING LAYER OF ELECTROCHEMICAL LIGHT EMITTING CELL Nippon Chemical Industrial Co., Ltd. (JP) 2018-10-10 EP disclosed
US-8569405-B2 Additive mixtures for styrenic polymers BASF SE (DE) 2013-10-29 US disclosed
US-8518302-B2 Stabilization of organic materials BASF SE (DE) 2013-08-27 US disclosed
US-20120088869-A1 STABILIZATION OF ORGANIC MATERIALS GERSTER MICHELE (CH) 2012-04-12 US disclosed
US-20120073661-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-03-29 US disclosed
US-20120073661-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-03-29 US disclosed
US-8105504-B2 Stabilization of organic materials BASF SE (DE) 2012-01-31 US disclosed
US-5356966-A Stabilizing organic material against oxidative, thermal or light iinduced degradation CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
EP-0608198-A1 Cyclic diphenylacetonenitriles as stabilisers CIBA-GEIGY AG (CH) 1994-07-27 EP disclosed
EP-0591102-A1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-04-06 EP disclosed
EP-0589839-A1 3-(Dihydrobenzofuran-5-yl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-03-30 EP disclosed
WO-1993013089-A1 MACROCYCLIC POLYETHER CARBOXYLIC ACIDS URBAN FRANK J (US) 1993-07-08 WO disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed
US-4935442-A Tetrahydrofuran-containing macrocyclic polyether carboxylic acids PFIZER INC. (US) 1990-06-19 US disclosed
US-4876367-A ANIMAL GROWTH REGULATORS PFIZER INC. (US) 1989-10-24 US disclosed
US-4777270-A INCREASE EFFICIENCY OF FEED UTILIZATION IN RUMINANTS PFIZER INC. (US) 1988-10-11 US disclosed
US-3992435-A USED FOR THE FORMATION OF POLYESTERS STANDARD OIL COMPANY (INDIANA) (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10930872-B2 Light-emitting electrochemical cell, composition for forming light-emitting layer of light-emitting electrochemical cell, and ionic compound for light-emitting layer of light-emitting electrochemical cell CRY2, CRY1, L1CAM RXRB 748/4885CYP3A4 1451/4885ACHE 3043/4885
US-20120088869-A1 STABILIZATION OF ORGANIC MATERIALS LPO, AOX1, SOD1 RXRB 2042/4885CYP3A4 500/4885ACHE 1442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.