Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561209 | 0.75 | KCNH3 (0.52) | NPSR1MEN1LMNAKMT2ATDP1 | |
| SCHEMBL797045 | 0.75 | KCNH3 (0.52) | NPSR1MEN1LMNAKMT2ATDP1 | |
| SCHEMBL29904069 | 0.73 | KCNH3 (0.40) | MEN1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL795752 | 0.72 | KMT2A (0.43) | NPSR1MEN1LMNAKMT2ATDP1 | |
| SCHEMBL795751 | 0.70 | L3MBTL1 (0.45) | NPSR1MEN1LMNAKMT2ATDP1 | |
| SCHEMBL3749726 | 0.69 | NR1H4 (0.50) | NPSR1L3MBTL1HDAC6HDAC1HDAC8 | |
| SCHEMBL795285 | 0.67 | NPSR1 (0.38) | NPSR1L3MBTL1DGAT1HDAC6HDAC1 | |
| SCHEMBL795269 | 0.66 | EPHX2 (0.39) | NPSR1MEN1LMNAKMT2ATDP1 | |
| SCHEMBL796256 | 0.66 | ROCK1 (0.42) | LMNAL3MBTL1HDAC6HDAC1HDAC8 | |
| SCHEMBL794750 | 0.64 | SYK (0.41) | MGAT2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933585-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-08-23 | — | — | CN | disclosed |