SCHEMBL2990416

SCHEMBL2990416

Cc1cc(C(F)(F)F)cc(C(=O)Nc2ccc3c(c2)C[C@H](NC(=O)O)C3)c1-c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MTTP P55157 15/20 0.67
APOB P04114 15/20 0.67
SMO Q99835 7/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5961560 0.87 SMO (0.85) MTTPAPOBSMO
SCHEMBL13591618 0.82 SMO (0.82) MTTPAPOBSMO
SCHEMBL7561317 0.81 MTTP (0.78) MTTPAPOBSMO
SCHEMBL13591616 0.79 SMO (1.00) MTTPAPOBSMO
SCHEMBL7505684 0.79 MTTP (0.59) MTTPAPOBSMO
SCHEMBL4785948 0.79 MTTP (1.00) MTTPAPOBSMO
SCHEMBL7038523 0.79 MTTP (1.00) MTTPAPOBSMO
SCHEMBL10205353 0.79 MTTP (1.00) MTTPAPOBSMO
SCHEMBL7515374 0.78 MTTP (0.57) MTTPAPOBSMO
SCHEMBL7035865 0.78 SMO (0.79) MTTPAPOBSMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100179182-A1 PHARMACEUTICAL FORMULATION SHMEIS RAMA ALI ABU 2010-07-15 US disclosed