Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442549 | 0.98 | KDM4E (0.47) | KDM4ECSNK2A1METAP2TTRTPMT | |
| SCHEMBL27304138 | 0.81 | KDM4E (0.47) | KDM4ECSNK2A1METAP2TTRTPMT | |
| SCHEMBL2988901 | 0.80 | LCK (0.56) | KDM4ECYP2D6ALDH1A1HSD17B10LMNA | |
| SCHEMBL29162781 | 0.80 | LCK (0.56) | KDM4ETTRTPMTCYP2D6CA1 | |
| SCHEMBL6563246 | 0.80 | CYP2D6 (0.47) | KDM4ECYP2D6CA1CA2ALDH1A1 | |
| SCHEMBL3442546 | 0.79 | CA1 (0.38) | KDM4EMETAP2TTRTPMTCA1 | |
| SCHEMBL411654 | 0.78 | ALDH1A1 (0.44) | KDM4ECSNK2A1CYP2D6CA1CA2 | |
| SCHEMBL28809636 | 0.78 | CYP2D6 (0.42) | KDM4ECYP2D6CA1CA2ALDH1A1 | |
| SCHEMBL2990424 | 0.78 | LCK (0.54) | KDM4ECYP2D6ALDH1A1HSD17B10LMNA | |
| SCHEMBL29987732 | 0.78 | KDM4E (0.44) | KDM4ECSNK2A1CYP2D6ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482680-C | excitatory amino acid prodrugs | LILLY CO ELI (US) | 2009-04-29 | — | — | CN | disclosed |
| CN-101084236-A | excitatory amino acid prodrugs | LILLY CO ELI (US) | 2007-12-05 | — | — | CN | disclosed |
| CN-1989140-A | Compounds containing a n-heteroaryl moiety linked to fused ring moieties for the inhibition of nad(p)h oxidases and platelet activation | VASOPHARM BIOTECH GMBH (DE) | 2007-06-27 | — | — | CN | disclosed |
| US-6927008-B2 | Photosensitive transfer material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-08-09 | — | — | US | disclosed |
| US-20040106061-A1 | Photosensitive transfer material | FUJI PHOTO FILM CO., LTD. | 2004-06-03 | — | — | US | disclosed |