SCHEMBL29904332

SCHEMBL29904332

C=CC(=O)N[C@@H](Cc1ccc(OC(=O)C=C)cc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.49
THRB P10828 2/20 0.49
ITGB1 P05556 3/20 0.48
ITGA4 P13612 3/20 0.48
ITGB7 P26010 3/20 0.48
ACACB O00763 1/20 0.45
CA2 P00918 2/20 0.44
GPR34 Q9UPC5 2/20 0.44
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43
NOS2 P35228 1/20 0.43
KMT2A Q03164 1/20 0.43
FPR2 P25090 1/20 0.42
MME P08473 2/20 0.42
ACE P12821 2/20 0.42
CPA1 P15085 2/20 0.42
ACE2 Q9BYF1 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20446064 0.89 SLC7A5 (0.52) PPARGITGB1ITGA4ITGB7CA2
SCHEMBL20446065 0.89 SLC7A5 (0.52) PPARGITGB1ITGA4ITGB7CA2
SCHEMBL20446062 0.89 SLC7A5 (0.52) PPARGITGB1ITGA4ITGB7CA2
SCHEMBL1097343 0.82 FOLH1 (0.57) CA2NOS2KMT2AMMEACE
SCHEMBL1097344 0.82 FOLH1 (0.57) CA2NOS2KMT2AMMEACE
SCHEMBL30511891 0.82 FOLH1 (0.57) CA2NOS2KMT2AMMEACE
SCHEMBL29214532 0.82 MME (0.58) NOS2FPR2MMEACECPA1
SCHEMBL1135185 0.82 MME (0.58) NOS2FPR2MMEACECPA1
SCHEMBL1135183 0.82 MME (0.58) NOS2FPR2MMEACECPA1
SCHEMBL20446011 0.81 CA2 (0.53) PPARGCA2NOS2MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-220095823-U Door plate and IP woven fabric with multilayer composite and special flower-shaped textures 旷达汽车饰件系统有限公司 2023-11-28 CN claimed
EP-4581152-A1 ANTIBODY SCREENING The Johns Hopkins University (US) 2025-07-09 EP disclosed
WO-2024049864-A9 ANTIBODY SCREENING THE JOHNS HOPKINS UNIVERSITY (US) 2025-04-03 WO disclosed
WO-2024049864-A1 ANTIBODY SCREENING THE JOHNS HOPKINS UNIVERSITY (US) 2024-03-07 WO disclosed
EP-3204118-B1 TREATMENT OF CARDIOVASCULAR DISEASE USING ACTRII LIGAND TRAPS CELGENE CORP (US) 2024-03-06 EP disclosed
US-11857379-B2 Force sensed surface scanning systems, devices, controllers and methods KONINKLIJKE PHILIPS N.V. (NL) 2024-01-02 US disclosed
CN-220095823-U Door plate and IP woven fabric with multilayer composite and special flower-shaped textures 旷达汽车饰件系统有限公司 2023-11-28 CN disclosed
US-11813308-B2 Treatment of cardiovascular disease using ActRII ligand traps CELGENE CORPORATION (MO) 2023-11-14 US disclosed
US-20230149115-A1 FORCE SENSED SURFACE SCANNING SYSTEMS, DEVICES, CONTROLLERS AND METHODS KONINKLIJKE PHILIPS NV (NL) 2023-05-18 US disclosed
CN-115841879-A Accurate monitoring method for group book implementing personnel based on city codes 太极计算机股份有限公司 2023-03-24 CN disclosed
US-11564768-B2 Force sensed surface scanning systems, devices, controllers and method KONINKLIJKE PHILIPS N.V. (NL) 2023-01-31 US disclosed
WO-2022216079-A1 GUCY2C BINDING POLYPEPTIDE AND USES THEREOF 주식회사 엘지화학 2022-10-13 WO disclosed