Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 8/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904457 | 0.79 | HSPA5 (0.71) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL8558332 | 0.79 | HSPA5 (0.71) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL10253049 | 0.77 | NPC1 (0.57) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL10287176 | 0.75 | NPC1 (0.53) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL7208136 | 0.74 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL29475123 | 0.74 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL3569428 | 0.74 | NPC1 (0.71) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL375488 | 0.73 | STAT3 (0.58) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16465542 | 0.73 | NPC1 (0.97) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL8562358 | 0.73 | NPC1 (0.56) | NPC1RAB9ALMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785100-A | Compounds useful as RET inhibitors | 癌症研究科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-110506043-B | Compounds useful as RET inhibitors | 癌症研究科技有限公司 | 2022-11-01 | — | — | CN | disclosed |