Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499578 | 1.00 | HTT (0.56) | HTTLMNATHRBKDM4EMEN1 | |
| SCHEMBL588770 | 1.00 | HTT (0.56) | HTTLMNATHRBKDM4EMEN1 | |
| SCHEMBL553501 | 0.83 | ALDH1A1 (0.59) | HTTLMNAKDM4EMEN1MAPT | |
| SCHEMBL9618923 | 0.81 | IDO1 (0.50) | HTTLMNATHRBKDM4EMEN1 | |
| SCHEMBL27497018 | 0.80 | ALDH1A1 (0.43) | HTTLMNATHRBKDM4EMEN1 | |
| SCHEMBL15961769 | 0.79 | HSD17B10 (0.50) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL1803989 | 0.78 | HSD17B10 (0.61) | HTTTHRBKDM4EMEN1MAPT | |
| SCHEMBL11153750 | 0.77 | HTT (0.52) | HTTLMNAKDM4EMEN1MAPT | |
| SCHEMBL21771152 | 0.77 | ALDH1A1 (0.49) | HTTLMNAKDM4EMEN1MAPT | |
| SCHEMBL6537307 | 0.77 | EP300 (0.46) | HTTLMNAKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115252588-B | Application of 1, 4-hydroquinone and/or 1, 4-hydroquinone derivative in preparing anti-novel coronavirus medicine | 山东达因海洋生物制药股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-115252588-A | Application of 1, 4-hydroquinone and/or 1, 4-hydroquinone derivative in preparation of anti-novel coronavirus medicines | 山东达因海洋生物制药股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115252588-B | Application of 1, 4-hydroquinone and/or 1, 4-hydroquinone derivative in preparing anti-novel coronavirus medicine | 山东达因海洋生物制药股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-115252588-A | Application of 1, 4-hydroquinone and/or 1, 4-hydroquinone derivative in preparation of anti-novel coronavirus medicines | 山东达因海洋生物制药股份有限公司 | 2022-11-01 | — | — | CN | disclosed |