SCHEMBL553501

SCHEMBL553501

Oc1c(Cl)cc(Cl)c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
KDM4E B2RXH2 4/20 0.59
MAPT P10636 4/20 0.59
HTT P42858 4/20 0.59
HSD17B10 Q99714 4/20 0.59
HPGD P15428 4/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
PKM P14618 2/20 0.59
CYP3A4 P08684 3/20 0.53
LMNA P02545 3/20 0.53
MMP14 P50281 3/20 0.53
TP53 P04637 2/20 0.53
HSP90AA1 P07900 2/20 0.53
ALOX15 P16050 2/20 0.53
ALOX12 P18054 2/20 0.53
SLC6A2 P23975 2/20 0.53
OPRK1 P41145 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
TDP1 Q9NUW8 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12192905 0.84 PKM (0.59) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL588770 0.83 HTT (0.56) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL29904657 0.83 HTT (0.56) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL30499578 0.83 HTT (0.56) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL10584076 0.83 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL6537307 0.79 EP300 (0.46) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL21771152 0.79 ALDH1A1 (0.49) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL11153750 0.79 HTT (0.52) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL23087330 0.79 HTT (0.53) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL30540374 0.79 HTT (0.63) ALDH1A1KDM4EMAPTHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417568-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF THE BOEING COMPANY (US) 2024-12-19 US claimed
EP-4477720-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF The Boeing Company (US) 2024-12-18 EP claimed
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US claimed
US-20240400732-A1 ETHYLENE-Alpha-OLEFIN COPOLYMER, PREPARATION METHOD THEREFOR, APPLICATION AND COMPOSITION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-12-05 US claimed
EP-4400522-A1 ETHYLENE-ALPHA-OLEFIN COPOLYMER, PREPARATION METHOD THEREFOR, APPLICATION AND COMPOSITION THEREOF China Petroleum & Chemical Corporation (CN) 2024-07-17 EP claimed
EP-4393962-A1 CATALYST COMPOSITION AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2024-07-03 EP claimed
CN-115894759-B Ethylene-alpha-olefin copolymer, preparation method and application thereof, and composition 中国石油化工股份有限公司 2024-07-02 CN claimed
CN-115894757-B Ethylene-enol copolymer and preparation method thereof 中国石油化工股份有限公司 2024-06-04 CN claimed
CN-115894758-B Ethylene-cycloolefin copolymer and process for producing the same 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-115894745-B Catalyst composition, olefin polymerization process and use 中国石油化工股份有限公司 2023-09-12 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-0620283-B1 Method for colourimetric determination of an analyte by using a PQQ-dependent dehydrogenase BOEHRINGER MANNHEIM GMBH (DE) 1998-09-16 EP claimed
US-5182213-A Coupling a Phenylenediamine and a Naphthol MILES INC. (US) 1993-01-26 US claimed
EP-0504663-A1 Peroxidase indicator system for basic media Bayer Corporation (US) 1992-09-23 EP claimed
US-4868275-A POLYTHIOETHERS TOSOH CORPORATION (JP) 1989-09-19 US claimed
EP-0304303-A2 Preparation of poly (arylene sulfide) Tosoh Corporation (JP) 1989-02-22 EP claimed
US-4784945-A Method for determining lipids BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1988-11-15 US claimed
US-4425404-A MULTILAYER, PROTECTIVE COATINGS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-01-10 US claimed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US claimed