SCHEMBL29904708

SCHEMBL29904708

Nc1ccc(C(=O)c2ccc(C(=O)O)cc2)cc1N

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 11/20 0.62
RARB P10826 1/20 0.50
RARG P13631 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 2/20 0.49
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CDC25B P30305 1/20 0.48
PBRM1 Q86U86 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28563770 1.00 SRD5A2 (0.62) SRD5A2RARBRARGRXRARXRB
SCHEMBL680167 0.89 MAPT (0.57) SRD5A2TSHRMAPK1GAAMAPT
SCHEMBL30874183 0.88 PBRM1 (0.62) SRD5A2MAPK1GAAMAPTALDH1A1
Benzophenone SCHEMBL27781305 0.88 PBRM1 (0.62) SRD5A2MAPK1GAAMAPTALDH1A1
SCHEMBL144914 0.88 PBRM1 (0.62) SRD5A2MAPK1GAAMAPTALDH1A1
SCHEMBL4824967 0.87 CDC25B (0.61) SRD5A2TP53TSHRGAAMAPT
SCHEMBL29351778 0.87 CDC25B (0.61) SRD5A2TP53TSHRGAAMAPT
Hydrochloric Acid SCHEMBL1600459 0.87 MAPT (0.55) SRD5A2TSHRMAPK1GAAMAPT
SCHEMBL77186 0.87 CDC25B (0.61) SRD5A2TP53TSHRGAAMAPT
SCHEMBL1898829 0.85 LMNA (0.50) SRD5A2MAPK1GAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117895038-A Fiber reinforced high-temperature proton exchange membrane, preparation method thereof and electrochemical equipment 坤艾新材料科技(上海)有限公司 2024-04-16 CN disclosed
CN-112820920-B High-temperature proton exchange membrane, preparation method and electrochemical equipment 坤艾新材料科技(上海)有限公司 2022-11-18 CN disclosed
CN-112820922-B Ceramic particle reinforced high-temperature proton exchange membrane, manufacturing method thereof and electrochemical equipment 坤艾新材料科技(上海)有限公司 2022-09-02 CN disclosed