Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.55 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680167 | 0.97 | MAPT (0.57) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10925606 | 0.89 | MAPK1 (0.47) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1898829 | 0.89 | LMNA (0.50) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28563770 | 0.87 | SRD5A2 (0.62) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL144914 | 0.87 | PBRM1 (0.62) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL931635 | 0.87 | HTT (0.62) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL30874183 | 0.87 | PBRM1 (0.62) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL29904708 | 0.87 | SRD5A2 (0.62) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| Benzophenone SCHEMBL27781305 | 0.87 | PBRM1 (0.62) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1599325 | 0.86 | PBRM1 (0.67) | MAPTMAPK1ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7704422-B2 | pyrolyzing the consolidated disks which contains polyimide and polybenzimidazole powder, in an inert atmosphere or carbon dioxide to form a monolithic porous carbon doped with metals; low cost production; high surface area, high pore volume, high surface activity, good mechanical properties | ELECTROMATERIALS, INC. (US) | 2010-04-27 | — | — | US | claimed |
| EP-1789364-A1 | PROCESSES FOR PRODUCING MONOLITHIC POROUS CARBON DISKS FROM AROMATIC ORGANIC PRECURSORS | Wang, Jing (US) | 2007-05-30 | — | — | EP | claimed |
| WO-2006023419-A1 | PROCESSES FOR PRODUCING MONOLITHIC POROUS CARBON DISKS FROM AROMATIC ORGANIC PRECURSORS | WANG JING (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060033226-A1 | Processes for producing monolithic porous carbon disks from aromatic organic precursors | ELECTROMATERIALS, INC. | 2006-02-16 | — | — | US | claimed |
| US-20060033225-A1 | pyrolyzing the consolidated disks which contains polyimide and polybenzimidazole powder, in an inert atmosphere or carbon dioxide to form a monolithic porous carbon doped with metals; low cost production; high surface area, high pore volume, high surface activity, good mechanical properties | ELECTROMATERIALS, INC. | 2006-02-16 | — | — | US | claimed |
| US-5443859-A | Reacting tetracarboxylic acid dianhydride, aromatic diamine, optionally polyamine, to form polyamic acid, forming film, imidizing to form polyimide, carbonizing in inert gas or vacuum to form carbon film with specifed properties | TOHO RAYON CO., LTD. (JP) | 1995-08-22 | — | — | US | claimed |
| US-7919024-B2 | Processes for producing monolithic porous carbon disks from aromatic organic precursors | ELECTROMATERIALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-7704422-B2 | pyrolyzing the consolidated disks which contains polyimide and polybenzimidazole powder, in an inert atmosphere or carbon dioxide to form a monolithic porous carbon doped with metals; low cost production; high surface area, high pore volume, high surface activity, good mechanical properties | ELECTROMATERIALS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20090220722-A1 | PROCESSES FOR PRODUCING MONOLITHIC POROUS CARBON DISKS FROM AROMATIC ORGANIC PRECURSORS | WANG JING | 2009-09-03 | — | — | US | disclosed |
| US-20090220826-A1 | PROCESSES FOR PRODUCING MONOLITHIC POROUS CARBON DISKS FROM AROMATIC ORGANIC PRECURSORS | WANG JING | 2009-09-03 | — | — | US | disclosed |
| US-20060033226-A1 | Processes for producing monolithic porous carbon disks from aromatic organic precursors | ELECTROMATERIALS, INC. | 2006-02-16 | — | — | US | disclosed |
| US-20060033225-A1 | pyrolyzing the consolidated disks which contains polyimide and polybenzimidazole powder, in an inert atmosphere or carbon dioxide to form a monolithic porous carbon doped with metals; low cost production; high surface area, high pore volume, high surface activity, good mechanical properties | ELECTROMATERIALS, INC. | 2006-02-16 | — | — | US | disclosed |
| US-6320019-B1 | REACTING A TETRACARBOXYLIC DIANHYDRIDE, AN AROMATIC DIAMINE, A DIAMINE WITH A SILOXANE STRUCTURE, AND AN AROMATIC TRI- OR TETRAAMINE WITH TWO PHENYL GROUPS | SAEHAN INDUSTRIES INCORPORATION (KR) | 2001-11-20 | — | — | US | disclosed |
| EP-0716113-B1 | Polyamic acid having three-dimensional network molecular structure, polyimide obtained therefrom and process for the preparation thereof | TOHO RAYON KK (JP) | 2000-01-19 | — | — | EP | disclosed |
| EP-0716113-A2 | Polyamic acid having three-dimensional network molecular structure, polyimide obtained therefrom and process for the preparation thereof | Toho Rayon Co., Ltd. (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5443859-A | Reacting tetracarboxylic acid dianhydride, aromatic diamine, optionally polyamine, to form polyamic acid, forming film, imidizing to form polyimide, carbonizing in inert gas or vacuum to form carbon film with specifed properties | TOHO RAYON CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| US-5352524-A | The carbon fiber sheet is derived from a polyimides of polyamic acid; tensile strength, electroconductivity, elasticity | TOHO RAYON CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| US-5231162-A | Polyamic acid having three-dimensional network molecular structure, polyimide obtained therefrom and process for the preparation thereof | TOHO RAYON CO. LTD. (JP) | 1993-07-27 | — | — | US | disclosed |