SCHEMBL29905110

SCHEMBL29905110

CC(C)(c1ccc(OC(=O)c2cccc(O)c2)cc1)c1ccc(OC(=O)c2cccc(O)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.60
ESR2 Q92731 3/20 0.60
MAPT P10636 4/20 0.56
TDP1 Q9NUW8 4/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KMT2A Q03164 8/20 0.50
MEN1 O00255 5/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
ALDH1A1 P00352 1/20 0.49
THRB P10828 1/20 0.49
SLC2A1 P11166 1/20 0.47
SLC2A4 P14672 1/20 0.47
CYP3A4 P08684 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21681864 1.00 ESR1 (0.60) ESR1ESR2MAPTTDP1L3MBTL1
SCHEMBL27636737 0.91 MAPT (0.69) ESR1ESR2MAPTTDP1L3MBTL1
SCHEMBL10875111 0.91 MAPT (0.56) ESR1ESR2MAPTTDP1L3MBTL1
SCHEMBL21681878 0.87 ESR1 (0.65) ESR1ESR2MAPTTDP1KMT2A
SCHEMBL2518984 0.86 MAPT (0.67) ESR1ESR2MAPTTDP1L3MBTL1
SCHEMBL14241103 0.86 MAPT (0.51) ESR1ESR2MAPTTDP1L3MBTL1
SCHEMBL13184050 0.86 KMT2A (0.62) ESR1ESR2MAPTTDP1L3MBTL1
SCHEMBL4859006 0.86 MAPT (0.55) ESR1ESR2MAPTTDP1L3MBTL1
SCHEMBL13184039 0.85 ESR1 (0.64) ESR1ESR2MAPTTDP1L3MBTL1
SCHEMBL13184001 0.85 KDM4E (0.50) ESR1ESR2MAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112119109-B Polycarbonate and method for producing same 株式会社LG化学 2022-09-06 CN disclosed