SCHEMBL4859006

SCHEMBL4859006

CC(C)(c1ccc(O)cc1)c1ccc(OC(=O)c2cccc(C(=O)O)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ESR1 P03372 6/20 0.48
ESR2 Q92731 5/20 0.48
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 2/20 0.46
KMT2A Q03164 4/20 0.46
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
CYP2C9 P11712 1/20 0.46
RAB9A P51151 1/20 0.46
MEN1 O00255 3/20 0.46
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL361198 0.97 MAPT (0.52) MAPTTDP1L3MBTL1ESR1ESR2
Bisphenol A SCHEMBL7055236 0.95 MAPT (0.56) MAPTTDP1L3MBTL1ESR1ESR2
Isophthalic Acid SCHEMBL1410762 0.95 MAPT (0.56) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL10875111 0.94 MAPT (0.56) MAPTTDP1L3MBTL1ESR1ESR2
Bisphenol A SCHEMBL6678074 0.91 KMT2A (0.50) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL9246472 0.90 MAPT (0.60) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL17889901 0.90 MAPT (0.51) MAPTTDP1L3MBTL1ESR1ESR2
Bicarbonate SCHEMBL9249849 0.89 MAPT (0.58) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL14241103 0.89 MAPT (0.51) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL9435811 0.89 CA12 (0.53) MAPTTDP1L3MBTL1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9441106-B2 Composition, multilayer sheets made therefrom, and methods for making and using the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-13 US claimed
US-9676939-B2 Heat resistant clear polycarbonate-polysiloxane compounds SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-13 US disclosed
EP-2691459-B1 IMPROVED HEAT RESISTANT CLEAR POLYCARBONATE-POLYSILOXANE COMPOUNDS SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-05-18 EP disclosed
US-20150307706-A1 HEAT RESISTANT CLEAR POLYCARBONATE-POLYSILOXANE COMPOUNDS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2015-10-29 US disclosed
US-9115283-B2 Heat resistant clear polycarbonate-polysiloxane compounds SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-08-25 US disclosed
EP-2691459-A1 IMPROVED HEAT RESISTANT CLEAR POLYCARBONATE-POLYSILOXANE COMPOUNDS SABIC Innovative Plastics IP B.V. (NL) 2014-02-05 EP disclosed
WO-2012134837-A1 IMPROVED HEAT RESISTANT CLEAR POLYCARBONATE-POLYSILOXANE COMPOUNDS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-10-04 WO disclosed
US-20120252985-A1 HEAT RESISTANT CLEAR POLYCARBONATE-POLYSILOXANE COMPOUNDS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-10-04 US disclosed
US-7459044-B2 Sheet material especially useful for circuit boards E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-02 US disclosed
EP-1423995-B1 SHEET MATERIAL AND ITS USE IN CIRCUIT BOARDS DU PONT (US) 2006-10-04 EP disclosed
US-6929848-B2 Sheet material especially useful for circuit boards E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-08-16 US disclosed
US-20050136233-A1 Sheet material especially useful for circuit boards SAMUELS MICHAEL R (US) 2005-06-23 US disclosed
US-20030087077-A1 Sheet material especially useful for circuit boards E. I. DU PONT DE NEMOURS AND COMPANY 2003-05-08 US disclosed
US-5502121-A VISUAL CLARITY FOR COATINGS AND MOLDINGS EASTMAN CHEMICAL COMPANY (US) 1996-03-26 US disclosed
US-4699956-A AROMATIC POLYESTER GENERAL ELECTRIC COMPANY (US) 1987-10-13 US disclosed
US-4585851-A BULK POLYMERIZATION OF DIARYL ESTERS, TRIARYL TRIMELLITATE AND DIPHENOL GENERAL ELECTRIC COMPANY (US) 1986-04-29 US disclosed
US-4454278-A ELECTRICAL INSULATION COATINGS GENERAL ELECTRIC COMPANY (US) 1984-06-12 US disclosed
US-4370447-A POLYCYCLIC CARBOXYLIC ACIDS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-01-25 US disclosed
EP-0030414-A1 Thermoplastic polymer compositions and shaped articles formed therefrom OCCIDENTAL CHEMICAL CORPORATION (US) 1981-06-17 EP disclosed