SCHEMBL29905756

SCHEMBL29905756

COc1ccc(/C=C/c2ccnc(-c3cc(/C=C/c4ccc(OC)cc4)ccn3)c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.65
KDM4E B2RXH2 2/20 0.65
NPC1 O15118 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP2D6 P10635 1/20 0.65
CYP2C9 P11712 1/20 0.65
HPGD P15428 1/20 0.65
CYP2C19 P33261 1/20 0.65
RAB9A P51151 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
KDM1A O60341 1/20 0.63
HDAC1 Q13547 1/20 0.63
HDAC6 Q9UBN7 1/20 0.63
CYP1A1 P04798 3/20 0.56
CYP1B1 Q16678 3/20 0.56
ESR1 P03372 2/20 0.56
TUBB4A P04350 2/20 0.56
TUBB P07437 2/20 0.56
TUBA3C P0DPH7 2/20 0.56
TUBA1B P68363 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400648 0.85 KDM1A (0.53) CYP1A2KDM4ENPC1CYP3A4CYP2D6
SCHEMBL26784184 0.84 CYP1A2 (0.62) CYP1A2KDM4ENPC1CYP3A4CYP2D6
SCHEMBL13400653 0.83 CYP1A2 (0.61) CYP1A2KDM4ENPC1CYP3A4CYP2D6
SCHEMBL29905764 0.83 RELA (0.62) CYP1A2CYP3A4CYP2D6CYP1A1CYP1B1
SCHEMBL2641826 0.83 CYP1A2 (0.61) CYP1A2KDM4ENPC1CYP3A4CYP2D6
SCHEMBL2641818 0.83 CYP1A2 (0.61) CYP1A2KDM4ENPC1CYP3A4CYP2D6
SCHEMBL18678714 0.82 KDM1A (0.58) CYP1A2KDM4ENPC1CYP3A4CYP2D6
SCHEMBL7604736 0.81 CYP1A1 (0.66) CYP1A2KDM4ECYP3A4CYP2D6CYP2C9
SCHEMBL14599365 0.80 KDM1A (0.56) CYP1A2KDM4ENPC1CYP3A4CYP2D6
SCHEMBL8050491 0.79 CYP1A2 (1.00) CYP1A2KDM4ENPC1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4054717-A1 METAL COMPLEXES BEARING BISSTYRYL-BIPYRIDINE LIGAND AND THEIR USE AS PHOTOSENSITIZER AGENT IN ONE AND TWO-PHOTON PHOTODYNAMIC THERAPY Paris Sciences et Lettres (FR) 2022-09-14 EP disclosed