Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844196 | 1.00 | MPO (0.40) | MPOHTR3AHPGDSHRH4HRH3 | |
| SCHEMBL29905984 | 1.00 | MPO (0.40) | MPOHTR3AHPGDSHRH4HRH3 | |
| SCHEMBL1726837 | 0.89 | CHEK1 (0.37) | HPGDS | |
| SCHEMBL16797026 | 0.89 | NR1H4 (0.38) | HRH4HRH3 | |
| SCHEMBL1886428 | 0.71 | SLC6A2 (0.36) | — | |
| SCHEMBL14683720 | 0.70 | MPO (0.40) | MPOHTR3AHPGDS | |
| SCHEMBL904372 | 0.70 | CHRNB4 (0.41) | HTR3A | |
| SCHEMBL12255455 | 0.67 | MPO (0.43) | MPOHTR3A | |
| SCHEMBL2281013 | 0.67 | HTR3A (0.46) | MPOHTR3A | |
| SCHEMBL12255456 | 0.67 | NOTUM (0.46) | MPOHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022211595-A1 | OXADIAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2022-10-06 | — | — | WO | disclosed |