Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptylacetate SCHEMBL27786255 | 0.97 | KDM4E (0.58) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Hexyl Acetate SCHEMBL27795514 | 0.91 | ALDH1A1 (0.61) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Acetic Acid Pentyl Ester SCHEMBL27372452 | 0.90 | ALDH1A1 (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Acetic Acid SCHEMBL28211368 | 0.89 | USP2 (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Heptylacetate SCHEMBL3680248 | 0.88 | ALDH1A1 (0.57) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glyceryl Monostearate SCHEMBL28148522 | 0.86 | KDM4E (0.80) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Cetyl Alcohol SCHEMBL27468473 | 0.85 | LMNA (0.59) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Cetostearyl Alcohol SCHEMBL27603933 | 0.85 | LMNA (0.59) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1002402 | 0.85 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL6452671 | 0.85 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115361948-A | Methods and compositions for inhibiting dihydroorotate dehydrogenase | 俄亥俄州国家创新基金会 | 2022-11-18 | — | — | CN | disclosed |
| CN-115335052-A | Methods and compositions for inhibiting dihydroorotate dehydrogenase in combination with anti-CD 38 therapeutics | 俄亥俄州国家创新基金会 | 2022-11-11 | — | — | CN | disclosed |
| CN-112672744-B | Methods and compositions for inhibiting dihydroorotate dehydrogenase | 俄亥俄州国家创新基金会 | 2022-10-14 | — | — | CN | disclosed |