SCHEMBL29906283

SCHEMBL29906283

CCCC[PH](CCCC)(CCCC)CCCC.O=C(O)c1cccc2[nH]nnc12

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
HPGD P15428 1/20 0.36
DHODH Q02127 5/20 0.36
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
RIPK1 Q13546 1/20 0.36
TSHR P16473 1/20 0.35
PARP1 P09874 2/20 0.35
MEN1 O00255 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34
PTPN6 P29350 1/20 0.34
CDC25B P30305 1/20 0.34
PTPN11 Q06124 1/20 0.34
ALDH1A1 P00352 1/20 0.33
MAPK8 P45983 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28136960 0.86 KDM4E (0.37) KDM4EHPGDDHODHCA12CA9
SCHEMBL29453826 0.83 KDM4E (0.47) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL170674 0.83 KDM4E (0.47) KDM4EHPGDDHODHPARP1ALDH1A1
Phosphine SCHEMBL4726258 0.82 KDM4E (0.46) KDM4EHPGDDHODHPARP1ALDH1A1
Ammonia Solution, Strong SCHEMBL6052082 0.82 KDM4E (0.46) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL9172345 0.82 KDM4E (0.46) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL3840407 0.82 KDM4E (0.46) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL26963405 0.81 TSHR (0.37) KDM4EHPGDDHODHCA12CA9
Ammonia Solution, Strong SCHEMBL11038589 0.80 KDM4E (0.45) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL10347683 0.80 KDM4E (0.45) KDM4EHPGDDHODHPARP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220298293-A1 ALIPHATIC POLYISOCYANATE COMPOSITION, PREPARATION METHOD THEREFOR, AND COATING COMPOSITION WANHUA CHEMICAL GROUP CO., LTD. (CN) 2022-09-22 US disclosed
EP-4056618-A1 ALIPHATIC POLYISOCYANATE COMPOSITION, PREPARARION METHOD THEREFOR, AND COATING COMPOSITION Wanhua Chemical Group Co., Ltd. (CN) 2022-09-14 EP disclosed