Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 11/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453826 | 0.98 | KDM4E (0.47) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| SCHEMBL170674 | 0.98 | KDM4E (0.47) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| Phosphine SCHEMBL4726258 | 0.96 | KDM4E (0.46) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| SCHEMBL9172345 | 0.96 | KDM4E (0.46) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL6052082 | 0.96 | KDM4E (0.46) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL11038589 | 0.95 | KDM4E (0.45) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| SCHEMBL10347683 | 0.95 | KDM4E (0.45) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| Phosphonic Acid SCHEMBL27792280 | 0.92 | KDM4E (0.43) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| Malonic Acid SCHEMBL8211370 | 0.90 | KDM4E (0.42) | KDM4EHPGDDHODHPARP1ALDH1A1 | |
| Benzotriazole SCHEMBL5506518 | 0.89 | ALDH1A1 (0.49) | KDM4EHPGDDHODHPARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1524257-B1 | Process for production of carboxylic acid aryl esters | JOHOKU CHEMICAL CO LTD (JP) | 2009-11-04 | — | — | EP | disclosed |
| EP-1174413-B1 | Process for production of carboxylic acid aryl esters | JOHOKU CHEMICAL CO LTD (JP) | 2005-11-02 | — | — | EP | disclosed |
| EP-1524258-A1 | Process for production of carboxylic acid aryl esters | Johoku Chemical Co., Ltd. (JP) | 2005-04-20 | — | — | EP | disclosed |
| EP-1524257-A1 | Process for production of carboxylic acid aryl esters | Johoku Chemical Co., Ltd. (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-6495712-B2 | REACTING A CARBOXYLIC ACID WITH (DI OR TRI)ARYL PHOSPHITE | JOHOKU CHEMICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| US-20020013491-A1 | Process for production of carboxylic acid aryl esters | JOHOKU CHEMICAL CO., LTD. (JP) | 2002-01-31 | — | — | US | disclosed |
| EP-1174413-A2 | Process for production of carboxylic acid aryl esters | Johoku Chemical Co., Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013491-A1 | Process for production of carboxylic acid aryl esters | GNPAT, AADAC, NAAA | KDM4E 1760/4885HPGD 1310/4885DHODH 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.