Phosphine

Phosphine

SCHEMBL4726258

O=C(O)c1cccc2[nH]nnc12.P

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
DHODH Q02127 11/20 0.45
PARP1 P09874 2/20 0.44
ALDH1A1 P00352 2/20 0.43
ALOX15 P16050 1/20 0.40
NAPRT Q6XQN6 1/20 0.39
PBRM1 Q86U86 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170674 0.98 KDM4E (0.47) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL29453826 0.98 KDM4E (0.47) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL3840407 0.96 KDM4E (0.46) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL9172345 0.96 KDM4E (0.46) KDM4EHPGDDHODHPARP1ALDH1A1
Ammonia Solution, Strong SCHEMBL6052082 0.96 KDM4E (0.46) KDM4EHPGDDHODHPARP1ALDH1A1
Ammonia Solution, Strong SCHEMBL11038589 0.95 KDM4E (0.45) KDM4EHPGDDHODHPARP1ALDH1A1
SCHEMBL10347683 0.95 KDM4E (0.45) KDM4EHPGDDHODHPARP1ALDH1A1
Phosphonic Acid SCHEMBL27792280 0.92 KDM4E (0.43) KDM4EHPGDDHODHPARP1ALDH1A1
Malonic Acid SCHEMBL8211370 0.90 KDM4E (0.42) KDM4EHPGDDHODHPARP1ALDH1A1
Benzotriazole SCHEMBL5506518 0.89 ALDH1A1 (0.49) KDM4EHPGDDHODHPARP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61293218-A None JP disclosed
EP-1669188-B1 Hose construction containing NBR elastomer composition and fluoroplastic barrier GOODYEAR TIRE & RUBBER (US) 2008-03-12 EP disclosed
US-20050003126-A1 Fuel hose TOKAI RUBBER INDUSTRIES, LTD. 2005-01-06 US disclosed
EP-1090935-B1 FLUOROCOPOLYMER AND COMPOSITION THEREOF ASAHI GLASS CO LTD (JP) 2005-01-05 EP disclosed
US-6833043-B1 Elastomer compositions for bonding to fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY 2004-12-21 US disclosed
US-6682796-B2 HAVING FLUORORESIN LAYER FORMED FROM COPOLYMER OF VINYLIDENE FLUORIDE AND CHLOROTRIFLUOROETHYLENE BY POWDER COATING, CONTAINING METAL SALT, ACRYLIC RUBBER, AND AMMONIUM/ PHOSPHONIUM SALT; HIGH GASOLINE IMPERMEABILITY, FLEXIBILITY TOKAI RUBBER INDUSTRIES, LTD. (JP) 2004-01-27 US disclosed
EP-1040164-B1 COMPOSITIONS FOR BONDING FLUOROPLASTICS DYNEON LLC (US) 2003-10-15 EP disclosed
EP-1037939-B1 ELASTOMER COMPOSITIONS FOR BONDING TO FLUOROPOLYMERS DYNEON LLC (US) 2003-09-03 EP disclosed
US-6482522-B1 Elastomer compositions for bonding to fluoropolymers DYNEON LLC 2002-11-19 US disclosed
US-20020006491-A1 Fluel hose TOKAI RUBBER INDUSTRIES, LTD. (JP) 2002-01-17 US disclosed
EP-1160496-A1 Fuel hose Tokai Rubber Industries, Ltd. (JP) 2001-12-05 EP disclosed
US-6300446-B1 Fluorine-containing copolymer and composition thereof ASAHI GLASS COMPANY, LIMITED (JP) 2001-10-09 US disclosed
US-6270901-B1 TOUGHNESS, HEAT RESISTANCE; FOR SEAL GASKETS AND LININGS, FILMS, GASKETS, TUBES OR HOSES, AND CONTAINERS DYNEON LLC 2001-08-07 US disclosed
EP-1101994-A2 Fuel hose Tokai Rubber Industries, Ltd. (JP) 2001-05-23 EP disclosed
EP-1090935-A1 FLUOROCOPOLYMER AND COMPOSITION THEREOF ASAHI GLASS COMPANY LTD. (JP) 2001-04-11 EP disclosed
EP-1040164-A1 COMPOSITIONS FOR BONDING FLUOROPLASTICS DYNEON LLC (US) 2000-10-04 EP disclosed
EP-1037939-A1 ELASTOMER COMPOSITIONS FOR BONDING TO FLUOROPOLYMERS DYNEON LLC (US) 2000-09-27 EP disclosed
WO-1999032542-A1 ELASTOMER COMPOSITIONS FOR BONDING TO FLUOROPOLYMERS DYNEON LLC (US) 1999-07-01 WO disclosed
WO-1999032557-A1 COMPOSITIONS FOR BONDING FLUOROPLASTICS DYNEON LLC (US) 1999-07-01 WO disclosed
JP-S61293218-A EPOXY RESIN CURING AGENT MATSUMOTO MASAKO 1986-12-24 JP disclosed