Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597730 | 1.00 | TRPV4 (0.37) | TRPV4ALDH1A1ADORA2AADORA1GAA | |
| SCHEMBL29196717 | 0.82 | TRPV4 (0.37) | TRPV4ALDH1A1ADORA2AADORA1GAA | |
| SCHEMBL186689 | 0.80 | TRPV4 (0.42) | TRPV4ALDH1A1ADORA2AADORA1GAA | |
| SCHEMBL29723241 | 0.78 | TRPV4 (0.34) | TRPV4ALDH1A1ADORA2AADORA1GAA | |
| SCHEMBL26928026 | 0.78 | TRPV4 (0.34) | TRPV4ALDH1A1ADORA2AADORA1GAA | |
| SCHEMBL24663165 | 0.78 | TRPV4 (0.34) | TRPV4ALDH1A1ADORA2AADORA1GAA | |
| SCHEMBL22288637 | 0.78 | TDP1 (0.32) | TRPV4ALDH1A1ADORA2AADORA1HSD17B10 | |
| SCHEMBL29424964 | 0.78 | TDP1 (0.32) | TRPV4ALDH1A1ADORA2AADORA1HSD17B10 | |
| SCHEMBL21047194 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL29682937 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215121-A1 | HEDGEHOG ACYLTRANSFERASE INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2025-10-16 | — | — | WO | disclosed |
| CN-120025321-A | Furan ring-containing compound, pharmaceutical composition and application thereof | 武汉熙瑞医药科技有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-119899188-A | METTL3 inhibitors | 杭州邦顺制药有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-116120287-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-116601131-A | CTPS1 inhibitor and application thereof | 林伯士克洛索有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116120287-A | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115052873-A | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2022-09-13 | — | — | CN | disclosed |