SCHEMBL299070

CCOC(=O)C(C)=CC1C(C(=O)Oc2c(C(C)(C)C)cc(C)cc2C(C)(C)C)C1(C)C.COC(=O)C(C)=CC1C(C)(C)C1(Cc1cccc(Oc2ccccc2)c1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	TDP1	Q9NUW8	3/20	0.46

▸	LMNA	P02545	2/20	0.42

▸	ADRA2A	P08913	1/20	0.42

▸	CNR1	P21554	1/20	0.42

▸	ATM	Q13315	1/20	0.42

▸	L3MBTL1	Q9Y468	1/20	0.42

▸	ALDH1A1	P00352	1/20	0.34

▸	CCR8	P51685	1/20	0.32

▸	MEN1	O00255	1/20	0.31

▸	KMT2A	Q03164	1/20	0.31

▸	CYP1A2	P05177	1/20	0.31

▸	TSHR	P16473	1/20	0.31

▸	CYP2C19	P33261	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5854351	0.80	TDP1 (0.45)	TDP1LMNAADRA2ACNR1ATM
SCHEMBL5854347	0.80	TDP1 (0.45)	TDP1LMNAADRA2ACNR1ATM
SCHEMBL295855	0.78	LMNA (0.48)	TDP1LMNAMEN1KMT2ACYP1A2
SCHEMBL295854	0.78	LMNA (0.48)	TDP1LMNAMEN1KMT2ACYP1A2
SCHEMBL296083	0.73	TDP1 (0.79)	TDP1LMNAADRA2ACNR1ATM
SCHEMBL296085	0.73	TDP1 (0.79)	TDP1LMNAADRA2ACNR1ATM
SCHEMBL296084	0.73	TDP1 (0.79)	TDP1LMNAADRA2ACNR1ATM
SCHEMBL299205	0.73	TDP1 (0.39)	TDP1LMNAADRA2ACNR1ATM
SCHEMBL23824720	0.72	TDP1 (0.54)	TDP1LMNAADRA2ACNR1ATM
SCHEMBL5854396	0.72	TDP1 (0.54)	TDP1LMNAADRA2ACNR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1683783-B1	Chiral copper complex and production processes thereof and using the same	SUMITOMO CHEMICAL CO (JP)	2012-03-14	—	—	EP	disclosed