Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 9/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210826 | 1.00 | DGAT1 (0.35) | DGAT1ALKABL1TGFBR1ACVR1 | |
| SCHEMBL23210922 | 0.90 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL29907079 | 0.90 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL29907089 | 0.88 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL23211052 | 0.88 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL23210912 | 0.84 | CTSA (0.37) | DGAT1 | |
| SCHEMBL29907115 | 0.84 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL23210803 | 0.84 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL29907099 | 0.84 | CTSA (0.37) | DGAT1 | |
| SCHEMBL23211110 | 0.78 | DGAT1 (0.42) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |