Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.35 |
| ▸ | CTSA | P10619 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210803 | 1.00 | DGAT1 (0.35) | DGAT1CTSAPDE10APIK3CDCHEK1 | |
| SCHEMBL23210912 | 0.90 | CTSA (0.37) | DGAT1CTSAPDE10A | |
| SCHEMBL29907099 | 0.90 | CTSA (0.37) | DGAT1CTSAPDE10A | |
| SCHEMBL29907003 | 0.84 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL23210826 | 0.84 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL23210830 | 0.83 | CTSA (0.34) | DGAT1CTSAPDE10APIK3CDS1PR1 | |
| SCHEMBL29907067 | 0.83 | CTSA (0.34) | DGAT1CTSAPDE10APIK3CDS1PR1 | |
| SCHEMBL23210922 | 0.82 | DGAT1 (0.41) | DGAT1CTSAGRIN2B | |
| SCHEMBL29907079 | 0.82 | DGAT1 (0.41) | DGAT1CTSAGRIN2B | |
| SCHEMBL30308862 | 0.82 | DGAT1 (0.34) | DGAT1CTSAGRIN2BJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |