Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 9/20 | 0.67 |
| ▸ | ACLY | P53396 | 2/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | SGK1 | O00141 | 3/20 | 0.46 |
| ▸ | CCR2 | P41597 | 3/20 | 0.46 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.45 |
| ▸ | CCR4 | P51679 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27143523 | 1.00 | PTGES2 (0.67) | PTGES2ACLYSLC40A1SGK1CCR2 | |
| SCHEMBL30897292 | 0.85 | PTGES2 (0.61) | PTGES2ACLYSLC40A1SGK1CCR2 | |
| Hydrochloric Acid SCHEMBL31588089 | 0.84 | PTGES2 (0.60) | PTGES2ACLYSLC40A1SGK1CCR2 | |
| SCHEMBL27146412 | 0.81 | PTGES2 (0.59) | PTGES2ACLYSLC40A1SGK1CCR2 | |
| SCHEMBL29907264 | 0.81 | PTGES2 (0.59) | PTGES2ACLYSLC40A1SGK1CCR2 | |
| SCHEMBL1265337 | 0.80 | PTGES2 (0.64) | PTGES2ACLYSLC40A1SGK1FSCN1 | |
| SCHEMBL3787762 | 0.80 | PTGES2 (1.00) | PTGES2ACLYSLC40A1SGK1CCR2 | |
| SCHEMBL27152893 | 0.79 | PTGES2 (0.57) | PTGES2ACLYSLC40A1SGK1CCR2 | |
| SCHEMBL29907245 | 0.78 | PTGES2 (0.56) | PTGES2ACLYCCR2CCR4 | |
| SCHEMBL27139881 | 0.78 | PTGES2 (0.56) | PTGES2ACLYCCR2CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177975-B | Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof | 蒙特利尔大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-120035595-A | Thiazolo [5,4-d ] pyrimidine compounds, compositions comprising the same and uses thereof | 蒙特利尔大学 | 2025-05-23 | — | — | CN | disclosed |
| EP-4326719-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-02-28 | — | — | EP | disclosed |
| EP-4326723-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-02-28 | — | — | EP | disclosed |
| CN-117177973-A | Pyrido [3,2-D ] pyrimidine compounds and their use for the treatment of proliferative disorders | 蒙特利尔大学 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022221939-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022221940-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2022-10-27 | — | — | WO | disclosed |