Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 9/20 | 0.59 |
| ▸ | ACLY | P53396 | 6/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SGK1 | O00141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27146412 | 1.00 | PTGES2 (0.59) | PTGES2ACLYPTK2BSMN1; SMN2SLC40A1 | |
| SCHEMBL29907245 | 0.87 | PTGES2 (0.56) | PTGES2ACLYCCR2 | |
| SCHEMBL27139881 | 0.87 | PTGES2 (0.56) | PTGES2ACLYCCR2 | |
| SCHEMBL29907260 | 0.81 | PTGES2 (0.67) | PTGES2ACLYSLC40A1CCR2SGK1 | |
| SCHEMBL27143523 | 0.81 | PTGES2 (0.67) | PTGES2ACLYSLC40A1CCR2SGK1 | |
| SCHEMBL27152893 | 0.76 | PTGES2 (0.57) | PTGES2ACLYSLC40A1CCR2SGK1 | |
| SCHEMBL7852262 | 0.74 | PTGES2 (0.68) | PTGES2ACLYSLC40A1PGRSGK1 | |
| SCHEMBL3787762 | 0.74 | PTGES2 (1.00) | PTGES2ACLYSLC40A1CCR2SGK1 | |
| SCHEMBL13875348 | 0.72 | PTGES2 (0.70) | PTGES2ACLYSLC40A1SGK1 | |
| SCHEMBL2146366 | 0.72 | PTGES2 (0.61) | PTGES2ACLYSLC40A1SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602047-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | The Universite de Montreal (CA) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |
| EP-4326723-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-02-28 | — | — | EP | disclosed |
| EP-4326719-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-02-28 | — | — | EP | disclosed |
| CN-117177973-A | Pyrido [3,2-D ] pyrimidine compounds and their use for the treatment of proliferative disorders | 蒙特利尔大学 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022221939-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022221940-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2022-10-27 | — | — | WO | disclosed |