Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30175498 | 0.85 | ADORA2A (0.45) | ADORA2AADORA1TGFBR1 | |
| SCHEMBL22552000 | 0.84 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907708 | 0.81 | TGFBR1 (0.51) | ADORA2AADORA1TGFBR1 | |
| SCHEMBL29907672 | 0.80 | ADORA2A (0.51) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21730242 | 0.80 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907796 | 0.80 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551951 | 0.79 | ADORA2A (0.80) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21730276 | 0.78 | ADORA2A (0.82) | ADORA2AADORA1ADORA2B | |
| SCHEMBL30880826 | 0.78 | TGFBR1 (0.41) | ADORA2AADORA1TGFBR1 | |
| SCHEMBL29907760 | 0.77 | IRAK4 (0.36) | ADORA2AADORA1ADORA2BTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |