Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.32 |
| ▸ | GLRB | P48167 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907672 | 0.79 | ADORA2A (0.51) | ADORA2AADORA2BADORA1 | |
| SCHEMBL29907604 | 0.77 | ADORA2A (0.61) | ADORA2AADORA2BADORA1TGFBR1 | |
| SCHEMBL29907731 | 0.74 | ADORA2A (0.52) | ADORA2AADORA2BADORA1DGAT1SOAT1 | |
| SCHEMBL29907725 | 0.74 | ADORA2A (0.54) | ADORA2AADORA2BADORA1 | |
| SCHEMBL29907696 | 0.73 | ADORA2A (0.46) | IRAK4ADORA2AADORA2BADORA1 | |
| SCHEMBL29907536 | 0.72 | ADORA2A (0.49) | ADORA2AADORA2BADORA1TGFBR1 | |
| SCHEMBL29907714 | 0.68 | ADORA2A (0.51) | ADORA2AADORA2BADORA1 | |
| SCHEMBL29906724 | 0.66 | SIRT6 (0.44) | GLRA3GLRB | |
| SCHEMBL3347772 | 0.65 | GLRA3 (0.44) | PIK3CBTLR8CCNCCDK8GLRA3 | |
| SCHEMBL5554203 | 0.65 | IL2 (0.46) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |