Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825784 | 0.75 | KCNJ1 (0.48) | KCNJ1 | |
| Iodide SCHEMBL28714110 | 0.72 | KCNJ1 (0.47) | KCNJ1 | |
| SCHEMBL28465086 | 0.68 | KDM4E (0.45) | KCNJ1 | |
| SCHEMBL23086941 | 0.67 | KCNJ1 (0.45) | KCNJ1 | |
| SCHEMBL30712023 | 0.67 | MAPT (0.47) | KCNJ1 | |
| SCHEMBL18472560 | 0.67 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL28630846 | 0.67 | TDP1 (0.49) | KCNJ1 | |
| SCHEMBL27858849 | 0.67 | MAPT (0.47) | KCNJ1 | |
| SCHEMBL8738123 | 0.66 | KCNJ1 (0.47) | KCNJ1 | |
| SCHEMBL30751854 | 0.66 | KCNJ1 (0.47) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |