SCHEMBL1825784

SCHEMBL1825784

O=Cc1cnc(C=O)cn1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 2/20 0.48
CCR1 P32246 1/20 0.39
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9797693 0.86 KCNJ1 (0.41) KCNJ1CCR1
SCHEMBL1206325 0.84
SCHEMBL5040448 0.84
SCHEMBL1913986 0.84
SCHEMBL9316936 0.84
SCHEMBL360899 0.84
SCHEMBL14941176 0.84
Pyridine SCHEMBL27962809 0.80 TSHR (0.41) KCNJ1ALDH1A1P2RX7
SCHEMBL12346040 0.80 KCNJ1 (0.38) KCNJ1
SCHEMBL23745087 0.78 HCAR3 (0.37) KCNJ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118620160-A Diazolyl sp2Carbon conjugated polymer and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-09-10 CN claimed
CN-117801373-A Preparation method and application of functionalized titanium dioxide 河南龙兴钛业科技股份有限公司 2024-04-02 CN claimed
CN-103896972-A Method for preparing chiral dual-core europium beta-diketone complex luminescent material UNIV ZHENGZHOU LIGHT IND 2014-07-02 CN claimed
CN-102089037-A Equilibrium dynamic mixtures containing stabilized hemiacetals for controlled release of active alcohols FIRMENICH & CIE 2011-06-08 CN claimed
CN-118620160-A Diazolyl sp2Carbon conjugated polymer and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-09-10 CN disclosed
CN-117801373-A Preparation method and application of functionalized titanium dioxide 河南龙兴钛业科技股份有限公司 2024-04-02 CN disclosed
CN-116789940-A Organic semiconductor material containing thiophene pyridine dione structure, preparation and application thereof 东华大学 2023-09-22 CN disclosed
US-11542397-B2 Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-03 US disclosed
US-11517565-B2 Bis-amines, compositions, and uses related to CXCR4 inhibition EMORY UNIVERSITY (US) 2022-12-06 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-114181265-A Chiral dual-core nickel nonlinear optical material and preparation method thereof 郑州轻工业大学 2022-03-15 CN disclosed
EP-3910003-A1 POLYAMIDE-IMIDE BLOCK COPOLYMER, METHOD FOR PREPARING SAME, AND POLYAMIDE-IMIDE FILM COMPRISING SAME LG Chem, Ltd. (KR) 2021-11-17 EP disclosed
EP-0202244-A1 CURED PRODUCTS FROM THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES. DOW CHEMICAL CO (US) 1986-11-26 EP disclosed
WO-1986006386-A1 THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1986-11-06 WO disclosed
US-4613663-A Thermoplastic and thermosettable products prepared by reacting nitrogen-containing heterocyclic compounds with aromatic aldehydes THE DOW CHEMICAL COMPANY (US) 1986-09-23 US disclosed
WO-1986002932-A1 THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1986-05-22 WO disclosed
US-4575542-A Thermosettable polystyrylpyridine prepolymer terminated with ethylenically unsaturated groups and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1986-03-11 US disclosed
US-4543388-A Thermosettable polymers or prepolymers prepared from polymethylated pyrazines and aromatic polyaldehydes and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1985-09-24 US disclosed
US-4260757-A Poly[di-1,2-(diazinylidene)-ethene-1,2-diols] WILEY RICHARD H 1981-04-07 US disclosed
US-4260757-A Poly[di-1,2-(diazinylidene)-ethene-1,2-diols] WILEY RICHARD H 1981-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11517565-B2 Bis-amines, compositions, and uses related to CXCR4 inhibition CXCR4, CXCL12, CXCR2 KCNJ1 3461/4885CCR1 13/4885ALDH1A1 453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.