Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907971 | 0.88 | LMNA (0.43) | LMNAMEN1KMT2ABCL2MCL1 | |
| SCHEMBL29907922 | 0.85 | LMNA (0.43) | LMNACHRNA7BCL2MCL1TRPA1 | |
| SCHEMBL29907954 | 0.83 | LMNA (0.41) | LMNABCL2MCL1TRPA1PTGS1 | |
| SCHEMBL29907991 | 0.80 | MAPT (0.46) | LMNAMEN1KMT2ADHFRMAPT | |
| SCHEMBL17229433 | 0.77 | LMNA (0.50) | LMNATRPA1PTGS1CACNA1CHPGD | |
| SCHEMBL21755906 | 0.75 | LMNA (0.48) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL21953832 | 0.74 | CHRNA7 (0.53) | LMNAMEN1KMT2ACHRNA7BCL2 | |
| SCHEMBL17232524 | 0.72 | LMNA (0.44) | LMNATRPA1PTGS1CACNA1CKDM4E | |
| SCHEMBL15878099 | 0.69 | IDH1 (0.61) | IDH1 | |
| SCHEMBL1431054 | 0.68 | RHEB (0.39) | LMNAMEN1KMT2ARXFP1RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989052-B | Guaiacol-austempering compound and preparation method thereof | 苏州大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-114989052-A | Guaiazuo thioether compound and preparation method thereof | 苏州大学 | 2022-09-02 | — | — | CN | disclosed |