Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907954 | 0.88 | LMNA (0.41) | LMNAADORA2ATRPA1PTGS1CACNA1C | |
| SCHEMBL29907971 | 0.88 | LMNA (0.43) | LMNAADORA2ATRPA1PTGS1CACNA1C | |
| SCHEMBL29907905 | 0.85 | LMNA (0.41) | LMNATRPA1PTGS1CACNA1CDHFR | |
| SCHEMBL29907991 | 0.80 | MAPT (0.46) | LMNADHFRALDH1A1KDM4EMAPT | |
| SCHEMBL17229433 | 0.79 | LMNA (0.50) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL21755906 | 0.78 | LMNA (0.48) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL17232524 | 0.74 | LMNA (0.44) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL26866970 | 0.72 | AGBL2 (0.38) | LMNAADORA2ATRPA1PTGS1CACNA1C | |
| SCHEMBL14002157 | 0.68 | CHRNA7 (0.53) | PTPN1CDC25ACDC25BDHFRALDH1A1 | |
| SCHEMBL15878674 | 0.68 | LMNA (0.53) | LMNATRPA1PTGS1CACNA1CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989052-B | Guaiacol-austempering compound and preparation method thereof | 苏州大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-114989052-A | Guaiazuo thioether compound and preparation method thereof | 苏州大学 | 2022-09-02 | — | — | CN | disclosed |