Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908212 | 0.90 | ROCK2 (0.30) | ROCK2 | |
| SCHEMBL29908228 | 0.87 | LRRK2 (0.33) | ROCK2ACACB | |
| SCHEMBL29627966 | 0.84 | EIF2AK4 (0.34) | ROCK2ACACB | |
| SCHEMBL29627919 | 0.83 | ROCK2 (0.37) | ROCK2 | |
| SCHEMBL29627918 | 0.81 | — | — | |
| SCHEMBL29908196 | 0.79 | ROCK2 (0.42) | ROCK2 | |
| SCHEMBL26290157 | 0.79 | ROCK2 (0.36) | ROCK2ACACB | |
| SCHEMBL25195353 | 0.78 | ROCK2 (0.38) | ROCK2 | |
| SCHEMBL29640830 | 0.78 | ROCK2 (0.38) | ROCK2 | |
| SCHEMBL29627860 | 0.78 | ROCK2 (0.38) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281841-A1 | ETHYNYLHETEROCYCLES AS RHO-ASSOCIATED COILED-COIL KINASE (ROCK) INHIBITORS | ANGION BIOMEDICA CORP. | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281841-A1 | ETHYNYLHETEROCYCLES AS RHO-ASSOCIATED COILED-COIL KINASE (ROCK) INHIBITORS | ROCK1, ROCK2, CIT | ROCK2 2/4885ACACB 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.