Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.64 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SCD | O00767 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836669 | 0.82 | KDR (0.68) | SMN1; SMN2SCDHDAC1NPC1LMNA | |
| SCHEMBL28573896 | 0.79 | STAT3 (1.00) | STAT3SMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL27569509 | 0.78 | HDAC1 (0.46) | STAT3SMN1; SMN2SCDHDAC1NPC1 | |
| SCHEMBL5835755 | 0.78 | CA2 (0.60) | SMN1; SMN2HDAC1NPC1LMNAPKM | |
| SCHEMBL4601021 | 0.76 | KDR (0.46) | PKMCCNE1CDK2KDR | |
| SCHEMBL4717243 | 0.76 | CA12 (0.49) | KDR | |
| SCHEMBL2650712 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1LMNAPKMRAB9A | |
| SCHEMBL13055703 | 0.74 | STAT3 (0.54) | STAT3DEGS1SMN1; SMN2SCDNPC1 | |
| Ammonia Solution, Strong SCHEMBL27867504 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1LMNAPKMRAB9A | |
| SCHEMBL25422503 | 0.73 | RAB9A (0.55) | SMN1; SMN2HDAC1NPC1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116456980-A | Application of thiazole compounds in preparation of medicines for treating and preventing cancers | 北京大学 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022206084-A1 | USE OF THIAZOLE COMPOUND IN PREPARATION OF DRUG FOR TREATING AND PREVENTING CANCER | 北京大学 | 2022-10-06 | — | — | WO | disclosed |