Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.80 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | DUSP22 | Q9NRW4 | 4/20 | 0.62 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.61 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.60 |
| ▸ | IKBKB | O14920 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795412 | 0.93 | APEX1 (0.70) | LCKAPEX1DUSP22PTPN12PTPN22 | |
| SCHEMBL3892654 | 0.92 | APEX1 (0.71) | LCKAPEX1DUSP22PTPN12PTPN22 | |
| SCHEMBL3892650 | 0.92 | APEX1 (0.71) | LCKAPEX1DUSP22PTPN12PTPN22 | |
| SCHEMBL29554158 | 0.92 | LCK (0.68) | LCKAPEX1DUSP22PTPN12PTPN22 | |
| SCHEMBL3896597 | 0.92 | LCK (0.68) | LCKAPEX1DUSP22PTPN12PTPN22 | |
| SCHEMBL3896603 | 0.92 | LCK (0.68) | LCKAPEX1DUSP22PTPN12PTPN22 | |
| SCHEMBL14426457 | 0.89 | LCK (1.00) | LCKAPEX1PIK3CGMEN1POLB | |
| SCHEMBL25865503 | 0.89 | LCK (1.00) | LCKAPEX1PIK3CGMEN1POLB | |
| SCHEMBL29697584 | 0.88 | DUSP22 (0.64) | LCKAPEX1DUSP22PTPN12PTPN22 | |
| SCHEMBL3892623 | 0.88 | PTPN12 (0.81) | LCKAPEX1DUSP22PTPN12PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057880-B | DLL3 monoclonal antibody | 四川大学华西医院 | 2022-09-09 | — | — | CN | disclosed |