SCHEMBL29908313

SCHEMBL29908313

C=Cc1ccc(C=C)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.46
TP53 P04637 1/20 0.46
ALDH1A1 P00352 4/20 0.46
TRPA1 O75762 1/20 0.39
MAPT P10636 2/20 0.35
PKM P14618 1/20 0.35
TSHR P16473 1/20 0.35
HDAC8 Q9BY41 2/20 0.34
PTGS1 P23219 4/20 0.33
PTGS2 P35354 4/20 0.33
ALOX5 P09917 3/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
TYMS P04818 1/20 0.33
TUBB1 Q9H4B7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
RECQL P46063 1/20 0.31
RAB9A P51151 1/20 0.31
MDM2 Q00987 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7086584 1.00 TDP1 (0.46) TDP1TP53ALDH1A1TRPA1MAPT
Water SCHEMBL20239044 0.98 TDP1 (0.45) TDP1TP53ALDH1A1TRPA1MAPT
SCHEMBL21317873 0.85 ALDH1A1 (0.35) TDP1TP53ALDH1A1PTGS1PTGS2
SCHEMBL10246772 0.85 ALDH1A1 (0.44) TDP1ALDH1A1MAPTTSHRPTGS2
SCHEMBL5126473 0.85 ALDH1A1 (0.45) TDP1TP53ALDH1A1TRPA1PKM
SCHEMBL6443461 0.83 TDP1 (0.45) TDP1TP53ALDH1A1MAPTTSHR
SCHEMBL21903040 0.81 TP53 (0.39) TDP1TP53ALDH1A1TRPA1MAPT
SCHEMBL29651844 0.81 TDP1 (0.46) TDP1TP53ALDH1A1TRPA1MAPT
SCHEMBL41439 0.81 TDP1 (0.46) TDP1TP53ALDH1A1TRPA1MAPT
SCHEMBL29407001 0.80 ALDH1A1 (0.50) TDP1TP53ALDH1A1TRPA1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4522406-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-19 EP claimed
CN-115785339-B Amino modified macroporous resin, polycarbonate with low carbamate content and preparation method thereof 万华化学集团股份有限公司 2025-02-18 CN claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
WO-2023218324-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-16 WO claimed
CN-115698776-A Insert material with high oxygen permeability coefficient and high refractive index 爱尔康公司 2023-02-03 CN claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
CN-115298574-A Embedded silicone hydrogel contact lenses 爱尔康公司 2022-11-04 CN claimed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 CN claimed
EP-4719750-A1 EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719753-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4683790-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-01-28 EP disclosed
WO-2025109468-A1 EMBEDDED CONTACT LENS WITH A HIGH REFRACTIVE INDEX INSERT THEREIN ALCON INC. (CH) 2025-05-30 WO disclosed
EP-4121802-A1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES Alcon Inc. (CH) 2023-01-25 EP disclosed
EP-4121801-A1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX Alcon Inc. (CH) 2023-01-25 EP disclosed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO disclosed
CN-115298574-A Embedded silicone hydrogel contact lenses 爱尔康公司 2022-11-04 CN disclosed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 CN disclosed
WO-2022208447-A1 EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-10-06 WO disclosed