Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823127 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1NPC1PKM | |
| SCHEMBL29908313 | 0.85 | TDP1 (0.46) | ALDH1A1TSHRTDP1TP53PKM | |
| SCHEMBL7086584 | 0.85 | TDP1 (0.46) | ALDH1A1TSHRTDP1TP53PKM | |
| SCHEMBL10246772 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1NPC1RAB9A | |
| Water SCHEMBL20239044 | 0.83 | TDP1 (0.45) | ALDH1A1TSHRTDP1TP53PKM | |
| SCHEMBL31511495 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1TP53NPC1 | |
| SCHEMBL4734817 | 0.78 | KDM4E (0.42) | ALDH1A1TDP1TP53RAB9ATYR | |
| SCHEMBL17345594 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRTP53NPC1PKM | |
| SCHEMBL17345601 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL21903040 | 0.76 | TP53 (0.39) | ALDH1A1TDP1TP53PKMTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956123-A | REACTING A STYRENE TYPE COMPOUND WITH A DIHALOACYL PEROXIDE TO MAKE A FLUOROALKYLAROMATIC ESTER | NIPPON OILS & FATS COMPANY, LTD. (JP) | 1990-09-11 | — | — | US | claimed |
| EP-0189275-B1 | METHOD FOR MANUFACTURE OF FLUORINE-CONTAINING AROMATIC DERIVATIVES | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-10-18 | — | — | EP | claimed |
| EP-0189275-A2 | Method for manufacture of fluorine-containing aromatic derivatives | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1986-07-30 | — | — | EP | claimed |
| WO-2025049767-A1 | AMIDE PRODRUGS AND USES THEREOF | AUTOBAHN THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-117285769-A | Reversible crosslinked polyethylene cable material and preparation method thereof | 中国石油天然气股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| WO-2023240938-A1 | REVERSIBLY CROSSLINKED POLYETHYLENE CABLE MATERIAL AND PREPARATION METHOD THEREFOR | 中国石油天然气股份有限公司 | 2023-12-21 | — | — | WO | disclosed |
| US-20150361053-A1 | 2 AMINO-3,4-DIHYDRCQUINAZOLINE DERIVATIVES AND THE USE THEREOF AS CATHEPSIN D INHIBITORS | MERCK PATENT GMBH (DE) | 2015-12-17 | — | — | US | disclosed |
| US-7449493-B2 | Diamines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMACEUTICAL COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-20050282882-A1 | Diamines as modulators of chemokine receptor activity | CARTER PERCY | 2005-12-22 | — | — | US | disclosed |
| US-6974836-B2 | Diamines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-12-13 | — | — | US | disclosed |
| EP-1351924-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2003-10-15 | — | — | EP | disclosed |
| US-20030060459-A1 | Diamines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-03-27 | — | — | US | disclosed |
| WO-2002050019-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA CO. (US) | 2002-06-27 | — | — | WO | disclosed |
| US-4956123-A | REACTING A STYRENE TYPE COMPOUND WITH A DIHALOACYL PEROXIDE TO MAKE A FLUOROALKYLAROMATIC ESTER | NIPPON OILS & FATS COMPANY, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0189275-B1 | METHOD FOR MANUFACTURE OF FLUORINE-CONTAINING AROMATIC DERIVATIVES | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0189275-A2 | Method for manufacture of fluorine-containing aromatic derivatives | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1986-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282882-A1 | Diamines as modulators of chemokine receptor activity | CCL11, CCR1, CCR2 | ALDH1A1 419/4885TSHR 1807/4885TDP1 1435/4885 |
| US-20030060459-A1 | Diamines as modulators of chemokine receptor activity | CCL11, CCR1, CCR2 | ALDH1A1 296/4885TSHR 1900/4885TDP1 1296/4885 |
| US-20150361053-A1 | 2 AMINO-3,4-DIHYDRCQUINAZOLINE DERIVATIVES AND THE USE THEREOF AS CATHEPSIN D INHIBITORS | CTSD, CTSZ, CTSK | ALDH1A1 973/4885TSHR 4711/4885TDP1 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.