SCHEMBL29908366

SCHEMBL29908366

CCCCCCCCCCCCCCCCc1ncccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KCNH2 Q12809 2/20 0.43
DHFR P00374 1/20 0.38
HSD11B1 P28845 1/20 0.38
KDM4E B2RXH2 3/20 0.36
LMNA P02545 3/20 0.36
USP2 O75604 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.36
NPC1 O15118 1/20 0.36
HSP90AA1 P07900 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TBXAS1 P24557 1/20 0.36
PPARA Q07869 1/20 0.36
TRPV1 Q8NER1 3/20 0.36
LIPG Q9Y5X9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259075 1.00 TDP1 (0.47) TDP1L3MBTL1KCNH2DHFRHSD11B1
SCHEMBL11119746 1.00 TDP1 (0.47) TDP1L3MBTL1KCNH2DHFRHSD11B1
SCHEMBL4607711 1.00 TDP1 (0.47) TDP1L3MBTL1KCNH2DHFRHSD11B1
SCHEMBL29791423 1.00 TDP1 (0.47) TDP1L3MBTL1KCNH2DHFRHSD11B1
SCHEMBL28673468 1.00 TDP1 (0.47) TDP1L3MBTL1KCNH2DHFRHSD11B1
Water SCHEMBL3623340 0.98 TDP1 (0.46) TDP1L3MBTL1KCNH2DHFRHSD11B1
SCHEMBL15639197 0.98 TDP1 (0.49) TDP1L3MBTL1KCNH2DHFRHSD11B1
SCHEMBL9544351 0.93 L3MBTL1 (0.42) TDP1L3MBTL1KDM4ELMNANPC1
SCHEMBL10246570 0.85 PDE4A (0.39) L3MBTL1KDM4E
SCHEMBL11629358 0.84 HSD11B1 (0.44) TDP1L3MBTL1KCNH2HSD11B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118620244-A Preparation method and application of kneadable and space-maintained double-network hydrogel 上海市伤骨科研究所 2024-09-10 CN disclosed
CN-118354770-A Flavonoid derivatives having GABAA receptor activity and methods of use 罗特格斯新泽西州立大学 2024-07-16 CN disclosed
CN-118236560-A Drug coated balloon catheter for non-vascular stenosis 优敦力公司 2024-06-25 CN disclosed
CN-117987299-A Paenibacillus KY1249 capable of producing alginic acid lyase, microbial agent and application of microbial agent 蓝沛生物科技(广东)有限公司 2024-05-07 CN disclosed
WO-2023240081-A1 TREATMENT, AMELIORATION, AND/OR PREVENTION OF INFLAMMATORY AND AUTOIMMUNE DISEASES YALE UNIVERSITY (US) 2023-12-14 WO disclosed
EP-3164117-B1 ABUSE DETERRENT IMMEDIATE RELEASE FORMULATIONS COMPRISING NON-CELLULOSE POLYSACCHARIDES SpecGx LLC (US) 2023-09-06 EP disclosed
EP-4223286-A2 SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION SpecGx LLC (US) 2023-08-09 EP disclosed
EP-3154528-B1 SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION SpecGx LLC (US) 2023-04-05 EP disclosed
US-11617712-B2 Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides SpecGx LLC (US) 2023-04-04 US disclosed
US-11583493-B2 Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides SpecGx LLC (US) 2023-02-21 US disclosed
US-11517521-B2 Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides SpecGx LLC (US) 2022-12-06 US disclosed
US-11478426-B2 Abuse deterrent immediate release capsule dosage forms SpecGx LLC (US) 2022-10-25 US disclosed
US-11464741-B2 Spray dried compositions having different dissolution profiles and processes for their preparation SpecGx LLC (US) 2022-10-11 US disclosed