Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 9/20 | 0.36 |
| ▸ | CNR1 | P21554 | 8/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.36 |
| ▸ | TRPV2 | Q9Y5S1 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665594 | 1.00 | FTO (0.54) | FTOTRPA1CNR2CNR1TRPV1 | |
| Acetic Acid SCHEMBL5042300 | 0.93 | FTO (0.48) | FTOTRPA1CNR2CNR1TRPV1 | |
| SCHEMBL24124089 | 0.93 | FTO (0.50) | FTOTRPA1CNR2CNR1TRPV1 | |
| SCHEMBL7522231 | 0.90 | FTO (0.53) | FTOTRPA1CNR2CNR1TRPV1 | |
| SCHEMBL9008421 | 0.90 | FTO (0.52) | FTOTRPA1CNR2CNR1TRPV1 | |
| SCHEMBL7520930 | 0.90 | FTO (0.52) | FTOTRPA1CNR2CNR1TRPV1 | |
| SCHEMBL12251392 | 0.84 | FTO (0.42) | FTOTRPA1CNR2CNR1TRPV1 | |
| SCHEMBL30717253 | 0.83 | FTO (0.55) | FTOCNR2LMNAHTR2BTDP1 | |
| SCHEMBL24299405 | 0.83 | FTO (0.55) | FTOCNR2LMNAHTR2BTDP1 | |
| SCHEMBL772979 | 0.83 | FTO (0.55) | FTOCNR2LMNAHTR2BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250170161-A1 | INHIBIN SUBUNIT BETA E INHIBITOR AND METHODS OF USE THEREOF | RISEN (SHANGHAI) MEDICINAL TECHNOLOGY CO., LTD. (CN) | 2025-05-29 | — | — | US | disclosed |
| US-20240197603-A1 | METHODS AND COMPOSITIONS FOR TREATING HYPERPIGMENTATION DISORDERS | INST NAT SANTE RECH MED (FR) | 2024-06-20 | — | — | US | disclosed |
| WO-2022208123-A1 | METHODS AND COMPOSITIONS FOR TREATING HYPERPIGMENTATION DISORDERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2022-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250170161-A1 | INHIBIN SUBUNIT BETA E INHIBITOR AND METHODS OF USE THEREOF | INHA, IGF2BP1, IGF2BP2 | FTO 2654/4885TRPA1 4880/4885CNR2 4835/4885 |
| US-20240197603-A1 | METHODS AND COMPOSITIONS FOR TREATING HYPERPIGMENTATION DISORDERS | SLC9A5, SLC25A3, SLC30A5 | FTO 649/4885TRPA1 2598/4885CNR2 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.