Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | YES1 | P07947 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824770 | 0.82 | SRC (0.41) | SRCGRIA1CACNG8ALDH1A1CYP1A2 | |
| SCHEMBL8050742 | 0.81 | GRIA1 (0.44) | SRCGRIA1CACNG8ALDH1A1HSP90AA1 | |
| SCHEMBL20072696 | 0.78 | GRIA1 (0.47) | SRCGRIA1CACNG8ALDH1A1AHR | |
| SCHEMBL29256281 | 0.78 | GRIA1 (0.37) | SRCGRIA1CACNG8ALDH1A1CYP1A2 | |
| SCHEMBL1815223 | 0.77 | GRIA1 (0.40) | SRCGRIA1CACNG8ALDH1A1AHR | |
| SCHEMBL15637198 | 0.77 | CYP2A6 (0.52) | ALDH1A1CYP2A6LMNA | |
| SCHEMBL1047283 | 0.75 | PBRM1 (0.42) | SRCGRIA1CACNG8ALDH1A1CYP1A2 | |
| SCHEMBL15637269 | 0.74 | TTR (0.38) | CYP1A2PBRM1 | |
| SCHEMBL4448776 | 0.74 | AHR (0.46) | SRCGRIA1CACNG8ALDH1A1HSP90AA1 | |
| SCHEMBL4453583 | 0.72 | AHR (0.64) | SRCGRIA1CACNG8ALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197736-A1 | CETP ACTIVITY INHIBITORS | JAPAN TOBACCO INC. (JP) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197736-A1 | CETP ACTIVITY INHIBITORS | CETP, MTTP, CES1 | SRC 2061/4885GRIA1 4126/4885CACNG8 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.