SCHEMBL1047283

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29116274	0.82	CA2 (0.39)	PBRM1HPGDCYP2D6CYP2C9ALOX15
	SCHEMBL14887253	0.81	ALDH1A1 (0.42)	PBRM1HPGDCYP2D6CYP2C9ALOX15
	SCHEMBL7636229	0.80	GRIA1 (0.52)	HPGDGRIA1CACNG8ALDH1A1KDM4E
	SCHEMBL1046307	0.80	AHR (0.54)	HPGDCYP2D6CYP2C9ALOX15CYP2C19
	SCHEMBL20904470	0.80	AHR (0.42)	HPGDCYP2D6CYP2C9ALOX15CYP2C19
	SCHEMBL1047922	0.79	CNR2 (0.50)	CYP2A6
	SCHEMBL1044029	0.79	ACHE (0.44)	GRIA1CACNG8SRCTDP1ACHE
	SCHEMBL4456487	0.79	CYP1A2 (0.50)	HSD17B10GRIA1CACNG8FABP3FABP4
	SCHEMBL20072696	0.78	GRIA1 (0.47)	GRIA1CACNG8SRCTDP1ALDH1A1
	SCHEMBL14670464	0.76	GRIA1 (0.39)	HPGDCYP2D6GRIA1CACNG8L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.