Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320359 | 0.74 | TTR (0.42) | TTRPTPN1MAOAMAOBMEN1 | |
| SCHEMBL18602048 | 0.64 | MAPT (0.73) | PTPN1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL16299685 | 0.64 | — | — | |
| SCHEMBL2717300 | 0.64 | — | — | |
| SCHEMBL28813644 | 0.63 | MAOA (0.59) | TTRPTPN1MAOAMAOBMEN1 | |
| SCHEMBL14336079 | 0.61 | PTPN1 (0.38) | PTPN1MAOAMAOBMEN1MAPT | |
| SCHEMBL5307719 | 0.61 | MAOA (0.39) | TTRPTPN1MAOAMAOBMEN1 | |
| SCHEMBL3058451 | 0.61 | NR3C1 (0.50) | TTRMAOAMAPTKMT2AALDH1A1 | |
| SCHEMBL10362225 | 0.60 | CYP19A1 (0.70) | TTRMAOAMAOBMEN1MAPT | |
| SCHEMBL3846047 | 0.60 | CYP19A1 (0.70) | TTRMAOAMAOBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444101-B | Cyclopentane chromanone spliced bis-spiro-indene dione oxoindole compound and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| WO-2022177263-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASES, COMPRISING DIAPORTHEONE A1, DIAPORTHEONE A2, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, OR COMBINATION THEREOF | 가천대학교 산학협력단 | 2022-08-25 | — | — | WO | disclosed |