Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601727 | 1.00 | EGFR (0.42) | EGFRCSF1RSMN1; SMN2TP53MAPT | |
| SCHEMBL29909622 | 0.89 | TACR1 (0.40) | SMN1; SMN2TACR1ABCG2KIF11 | |
| SCHEMBL23577126 | 0.89 | TACR1 (0.40) | SMN1; SMN2TACR1ABCG2KIF11 | |
| SCHEMBL29909212 | 0.85 | KIF11 (0.39) | EGFRCSF1RSMN1; SMN2TP53MAPT | |
| SCHEMBL23577152 | 0.85 | KIF11 (0.39) | EGFRCSF1RSMN1; SMN2TP53MAPT | |
| SCHEMBL23577419 | 0.85 | ABCG2 (0.52) | SMN1; SMN2ABCG2HTR6 | |
| SCHEMBL31229721 | 0.85 | ABCG2 (0.52) | SMN1; SMN2ABCG2HTR6 | |
| SCHEMBL23577319 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2ABCG2 | |
| SCHEMBL29909117 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2ABCG2 | |
| SCHEMBL23577241 | 0.84 | MAPT (0.43) | EGFRCSF1RSMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |