Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577319 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2ABCG2GRM2ACP1DYRK1A | |
| SCHEMBL29909776 | 0.87 | DYRK1A (0.44) | SMN1; SMN2DYRK1A | |
| SCHEMBL23601282 | 0.87 | DYRK1A (0.44) | SMN1; SMN2DYRK1A | |
| SCHEMBL29909006 | 0.84 | EGFR (0.42) | SMN1; SMN2ABCG2 | |
| SCHEMBL23601727 | 0.84 | EGFR (0.42) | SMN1; SMN2ABCG2 | |
| SCHEMBL23577419 | 0.82 | ABCG2 (0.52) | SMN1; SMN2ABCG2PDE5A | |
| SCHEMBL31229721 | 0.82 | ABCG2 (0.52) | SMN1; SMN2ABCG2PDE5A | |
| SCHEMBL23576748 | 0.81 | CYP1A2 (0.44) | SMN1; SMN2ABCG2DYRK1APDE5A | |
| SCHEMBL29909727 | 0.81 | CYP1A2 (0.44) | SMN1; SMN2ABCG2DYRK1APDE5A | |
| SCHEMBL23577241 | 0.81 | MAPT (0.43) | SMN1; SMN2ABCG2DYRK1APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |