Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576913 | 1.00 | HRH4 (0.36) | HRH4MAT2AMEN1KMT2APRMT5 | |
| SCHEMBL23601427 | 0.90 | MAT2A (0.36) | HRH4MAT2APRMT5CYP1A2PARP15 | |
| SCHEMBL29909955 | 0.83 | MAT2A (0.36) | HRH4MAT2AMEN1KMT2APRMT5 | |
| SCHEMBL23577423 | 0.83 | MAT2A (0.36) | HRH4MAT2AMEN1KMT2APRMT5 | |
| SCHEMBL23601441 | 0.83 | HRH4 (0.36) | HRH4MAT2AMEN1KMT2APRMT5 | |
| SCHEMBL31169447 | 0.82 | HRH4 (0.33) | HRH4MAT2AMEN1KMT2APRMT5 | |
| SCHEMBL29909627 | 0.82 | FNTA (0.35) | HRH4MAT2AMEN1KMT2APRMT5 | |
| SCHEMBL23576821 | 0.82 | FNTA (0.35) | HRH4MAT2AMEN1KMT2APRMT5 | |
| SCHEMBL23601026 | 0.82 | HRH4 (0.33) | HRH4MAT2AMEN1KMT2APRMT5 | |
| SCHEMBL23576693 | 0.82 | MAT2A (0.35) | HRH4MAT2AMEN1KMT2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |